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Spinal Cord Anatomy

Medulla spinalis

For medical students2 min readUpdated 2026-10-10

The spinal cord (medulla spinalis) is a phylogenetically older part of the central nervous system characterized by a distinct segmental organization. It performs critical functions: it connects the brain with peripheral structures and mediates segmental reflex activity.

Organ lengthAverages 40–45 cm in an adult
WeightTotal spinal cord weight is approximately 35 g
Number of segmentsConsists of 31 pairs of anatomical segments

General Characteristics and Matter Distribution

The spinal cord (medulla spinalis) is a long cord-like structure, ranging from 1.0 to 1.5 cm in width. The central canal (canalis centralis) runs through the center of the organ along its entire length.

A crucial anatomical feature is the uneven distribution of nervous tissue across different levels. The ratio of gray matter to white matter strictly depends on the region:

Gross Structure: Sulci and Fissures

The surface of the spinal cord is uneven, marked by longitudinal depressions that divide the organ into symmetrical halves.

On the anterior surface lies the deepest anterior median fissure (fissura mediana ventralis, or anterior). The intermediate cervical septum (septum cervicale intermedium) projects into this fissure.

On the posterior surface runs the posterior median sulcus (sulcus medianus dorsalis, or posterior). The posterior median septum (septum medianum dorsale) projects into this sulcus.

Each half of the spinal cord features lateral sulci:

Additionally, exclusively in the cervical and upper thoracic regions, an extra posterior intermediate sulcus (sulcus intermedius dorsalis, or posterior) is visible.

Segmental Structure and Enlargements

The organ has a metameric structure. A spinal cord segment (segmentum medullae spinalis) is the region that gives rise to exactly one pair of spinal nerves.

There are 31 segments in total, classified by regions:

  1. 8 cervical (segmenta cervicalia);
  2. 12 thoracic (segmenta thoracica);
  3. 5 lumbar (segmenta lumbalia);
  4. 5 sacral (segmenta sacralia);
  5. 1–3 coccygeal (segmenta coccygea).

The diameter of the spinal cord is not uniform throughout its length. It forms two major enlargements associated with limb innervation. The cervical enlargement (intumescentia cervicalis) corresponds to the upper limb innervation area. The lumbosacral enlargement (intumescentia lumbosacralis) functionally corresponds to the lower limb innervation zone.

Spinal Roots and Nerves

Each pair of spinal nerves (nervus spinalis) strictly corresponds to its segment and is mixed in function. The nerve is formed by the joining of two roots:

The sensory spinal ganglion (ganglion spinale, or sensorium) is located on the posterior root. Pseudounipolar neurons reside within this ganglion. The peripheral process of such a neuron extends to receptors in the periphery, while the central process enters the posterior root directly.

Frequently asked questions

What is a spinal cord segment?

It is an anatomical division of the spinal cord that gives rise to a single pair of spinal nerves. Humans have 31 such segments in total.

What structures form a spinal nerve?

A spinal nerve is formed by the merger of the anterior (motor) and posterior (sensory) roots, resulting in a mixed nerve.

How does the white-to-gray matter ratio change along the cord?

In the thoracic region, white matter exceeds gray matter by 10–12 times. However, in the lumbar region and particularly in the medullary cone, gray matter predominates.

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