Calendula and St. John's Wort Preparations
Calendula officinalis (Marigold) Preparations based on calendula flowers feature a rich complex of pharmacological effects. In addition to prominent antiseptic and bactericidal action (with specific activity against Trichomonas), they accelerate wound healing, suppress inflammation, and exert choleretic, sedative, and cardiotonic effects.
Methods of administration depend on the pathology:
- Topically (infusions and tinctures): in dentistry, used for rinsing in periodontal disease, gingivitis, and marked gingival bleeding. In ENT practice, for tonsillitis and pharyngitis. In gynecology, tinctures are used for douching in trichomonal colpitis and cervical erosion.
- Externally (ointments): in surgery and traumatology for treating furunculosis, burns, cuts, bruises, and minor wounds.
- Orally (extracts, tablets): in gastroenterology for peptic ulcer disease, gastritis, enterocolitis, and as a choleretic agent in biliary tract disorders.
Novoimanin The source of this drug is Hypericum perforatum (St. John's wort). Novoimanin exhibits antimicrobial activity directed primarily against gram-positive bacteria and effectively relieves inflammation. In purulent surgery, it is prescribed for the treatment of abscesses, phlegmon, pyoderma, infected wounds, trophic ulcers, and burns. In ENT practice, it is indicated for rhinitis, pharyngitis, sinusitis, and otitis. The primary side effect is the risk of developing allergic reactions.
Eucalyptus-Based Agents
Eucalyptus leaves are a potent source of antiseptics that eliminate gram-positive and gram-negative bacteria, fungi, and protozoa (amoebae, Trichomonas). The spectrum of effects includes pronounced antiseptic, expectorant, anti-inflammatory, and mild sedative actions.
- Infusions and Tinctures: versatile dosage forms. Externally (as rinses), they treat stomatitis, gingivitis, and tonsillitis. Inhalation is used for acute respiratory infections and respiratory tract conditions (tracheitis, laryngitis). Locally (compresses, wet tampons), they are used for purulent-inflammatory skin lesions (carbuncles, phlegmon, furuncles), trophic ulcers, burns, and frostbite. In gynecology, douching is prescribed for vaginitis, colpitis, and cervical ulcers.
- Chlorophyllipt (Chlorophyllipt): a mixture of chlorophylls isolated from eucalyptus leaves. The preparation possesses antibacterial activity and stimulates regenerative processes. Topically, it is used to anoint burns, trophic ulcers, and cervical erosions, and is applied in dental disorders (stomatitis, periodontitis). When taken orally, it exerts systemic effects: it exhibits specific activity against intestinal staphylococcal infections, pyelonephritis, and cholecystitis.
- Eucalimin (Eucalimin): available as an alcoholic solution. The active substance is a sum of aldehyde-phenol compounds from Eucalyptus viminalis. It exerts antibacterial, anti-inflammatory, and mild fungistatic (fungal growth-inhibiting) action.
Macleaya Alkaloids
The drug Sanguiritrin (Sanguiritrin) is obtained from plant materials—Macleaya cordata and Macleaya microcarpa. Chemically, it is a mixture of alkaloid bisulfates (sanguinarine and chelerythrine).
The spectrum of antimicrobial activity of the drug includes:
- Gram-positive and gram-negative bacteria.
- Fungi (dermatophytes and yeast-like fungi of the genus Candida).
Due to this broad coverage, sanguiritrin has found clinical application in treating diseases of mixed etiology, where purulent-inflammatory processes occur concurrently with fungal infections.