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Heart and Vena Cava System

Cor et venae cavae

For medical students2 min readUpdated 2026-10-10

The heart is a hollow muscular organ responsible for circulating blood through the vascular system. The superior and inferior vena cava systems collect deoxygenated blood from all parts of the body and return it to the right atrium, completing the systemic circulation.

Heart mass220–300 g (up to 450 g in athletes)
Left ventricular wall thickness11–14 mm (2–3 times thicker than the right)
Wall layersEpicardium, myocardium, endocardium
AnastomosesCaval-caval connections link the vena cava basins

Vena Cava Systems

Venous blood from organs and tissues returns to the heart via two major trunks: the superior and inferior venae cavae.

Important caval-caval anastomoses exist between these two systems, providing collateral venous drainage (e.g., via the epigastric veins of the anterior abdominal wall or the ascending lumbar veins).

External Structure and Cardiac Chambers

The heart is cone-shaped, with its base (basis cordis) directed superiorly and posteriorly, and its apex (apex cordis) directed inferiorly and anteriorly. Externally, sternocostal (anterior) and diaphragmatic (inferior) surfaces are distinguished. The boundaries between chambers are marked by sulci: the coronary sulcus and two interventricular sulci (anterior and posterior).

Internally, the organ is divided into four chambers:

  1. Right atrium (atrium dextrum) — receives blood from both venae cavae and the coronary sinus. The internal surface is partially lined by pectinate muscles. The interatrial septum features the fossa ovalis.
  2. Right ventricle (ventriculus dexter) — ejects blood into the pulmonary trunk. Separated from the atrium by the tricuspid valve. Features muscular trabeculae and papillary muscles.
  3. Left atrium (atrium sinistrum) — receives oxygenated blood from four pulmonary veins.
  4. Left ventricle (ventriculus sinister) — possesses the thickest wall, as it pumps blood into the aorta (systemic circulation). The bicuspid (mitral) valve is located between this chamber and the left atrium.

Wall Structure and Blood Supply

The heart wall consists of three layers: the inner endocardium (forming the valves), the thick muscular myocardium, and the outer epicardium (the visceral layer of the serous pericardium). The atrial and ventricular myocardium are separated by fibrous rings, with electrical connection between them occurring exclusively via the conduction system.

The heart is supplied by the right and left coronary arteries (aa. coronariae dextra et sinistra), which arise from the aortic sinuses (bulbus aortae):

Frequently asked questions

Where is the fossa ovalis located and what is its significance?

The fossa ovalis is located on the interatrial septum within the right atrium. It is the remnant of the fetal foramen ovale, which allowed blood to bypass the lungs by flowing directly from the right atrium to the left atrium in utero.

What is the difference in structure between the atrial and ventricular myocardium?

The atrial myocardium is thinner and consists of two layers (superficial and deep). The ventricular myocardium is thicker (especially on the left) and comprises three layers (superficial, middle circular, and deep).

What alternative pathways of venous drainage exist if one of the venae cavae is obstructed?

Blood can flow through caval-caval anastomoses: via the anterior abdominal wall (epigastric veins), subcutaneously (thoracoepigastric vein), and through the lumbar region (ascending lumbar veins, continuing into the azygos and hemiazygous systems).

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