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Mammary Gland

Mamma, glandula mammaria

For medical students2 min readUpdated 2026-10-10

The mammary gland is a paired cutaneous organ that embryologically represents a modified sweat gland. In females, it performs a vital secretory function (lactation), whereas in males it remains in a rudimentary state throughout life.

OriginModified sweat gland
TopographyLevel of III–VI ribs
Structure15–20 lobes within the glandular body
Lymphatic drainageTo the axillary lymph nodes

Topography and External Structure

The gland is located on the anterior thoracic wall. It lies on the surface of the pectoralis major muscle and partially extends over the serratus anterior muscle. The vertical boundaries of the organ extend from the level of the 3rd to the 6th rib, and the horizontal boundaries extend from the parasternal line to the anterior axillary line.

The external surface of the organ features characteristic structures:

Internal Structure

The basis of the organ is formed by the body of the mammary gland (corpus mammae). It has a lobular structure and consists of 15–20 lobes (lobi glandulae mammariae). Strong connective tissue septa are located between the lobes, forming the framework of the organ.

Each individual lobe is subdivided into smaller structures — lobules (lobuli glandulae mammariae). It is within these lobules that the alveolar-tubular secretory units responsible for milk production are located.

A lactiferous duct (ductus lactifer) extends from each lobe toward the center of the gland. Before entering the nipple and opening on its surface, each such duct forms a local dilation — the lactiferous sinus (sinus lactifer), which serves as a small reservoir for the secretion.

Coverings and Fixation Apparatus

The glandular tissue itself is surrounded on all sides by masses of adipose and fibrous tissue, which determine the shape and volume of the organ.

To support the organ on the anterior thoracic wall, specialized connective tissue strands exist — the suspensory ligaments of the breast (ligg. suspensoria mammaria). These dense structures securely anchor the gland to the deep layers of the skin and underlying fascia. The posterior surface of the gland is separated from the pectoral fascia by a layer of loose connective tissue, which provides the organ with a degree of mobility.

Characteristics of the Male Mammary Gland

In males, the organ is termed mamma masculina. Normally, it is completely rudimentary and does not perform secretory functions. The male gland is represented only by a small amount of connective tissue interspersed with poorly developed, non-functioning ducts.

Blood Supply, Innervation, and Lymphatic Drainage

The blood supply to the organ is characterized by a multiplicity of sources. Arterial blood is supplied from branches of:

  1. Internal thoracic artery (a. thoracica interna).
  2. Lateral thoracic artery (a. thoracica lateralis).
  3. Intercostal arteries.

Venous drainage is carried out via corresponding veins accompanying the arteries.

Innervation is provided by branches of the intercostal nerves (nn. intercostales) and supraclavicular nerves (nn. supraclaviculares).

The lymphatic system plays a critically important role. The primary bulk of lymph from the mammary tissue drains predominantly into the axillary lymph nodes (nodi lymphatici axillares).

Frequently asked questions

Where do the lactiferous ducts open at the apex of the nipple?

At the apex of the nipple, the lactiferous ducts open via lactiferous orifices. Distally (toward the tip), the ducts narrow, transition their epithelial type to stratified squamous keratinized epithelium, and emerge onto the surface. Notably, the number of openings ranges from 8 to 15, which is fewer than the number of lobes (15–20), as some ducts fuse with each other before emerging.

Which groups of lymph nodes receive lymph from the mammary gland?

Lymph from the mammary gland is received by several groups of lymph nodes forming the main drainage pathways.

  • Axillary lymph nodes (nodi lymphatici axillares) — receive about 75% of the lymph (predominantly from the lateral quadrants).
  • Paramammary lymph nodes (nodi lymphoidei paramammarii) — located along the lateral thoracic artery.
  • Interpectoral lymph nodes (nodi lymphoidei interpectorales) — situated between the pectoralis major and minor muscles.
  • Parasternal lymph nodes (nodi lymphatici parasternales) — receive lymph from the medial quadrants.
  • Supraclavicular lymph nodes — collect lymph from the superior regions of the gland.
  • Subclavicular nodes — receive lymph following the axillary nodes.
  • Intercostal lymph nodes — receive drainage from the posterior regions.
With which fascia and muscles does the posterior surface of the mammary gland come into contact?

The posterior surface of the mammary gland is separated from the fascia of the pectoral muscles by a layer of loose cellular tissue. The gland lies on the surface of the pectoralis major muscle and partially the serratus anterior muscle.

What glands are located in the skin of the areola?

Sebaceous and sweat glands are located in the skin of the areola.

  • Areolar glands (glandulae areolares) — a complex of sebaceous and sweat glands characteristic of this region.

Sebaceous glands in this zone have a unique feature: they are not associated with hair follicles, as hairs are absent on the areola. Inflammation of the areolar glands in clinical practice is termed areolitis.

What is the embryological origin of the mammary gland?

From a developmental standpoint, the mammary gland is a modified cutaneous sweat gland.

At the level of which ribs is the organ located?

Normally, the mammary gland is located at the level of the 3rd to 6th ribs.

Where does the primary lymphatic drainage occur?

Lymph drains predominantly into the axillary lymph nodes (nodi lymphatici axillares).

How many lobes are contained within the body of the mammary gland on average?

The body of the mammary gland consists of 15–20 lobes separated by connective tissue septa.

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