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Pterygopalatine Fossa

Fossa pterygopalatina

For medical students2 min readUpdated 2026-10-10

The pterygopalatine fossa (Fossa pterygopalatina) is a critical funnel-shaped space in the deep facial skeleton that acts as a major neurovascular distribution center. It contains key autonomic and sensory structures and communicates with several adjacent cavities through a system of foramina, fissures, and canals.

Parasympathetic GanglionPterygopalatine ganglion (*Ganglion pterygopalatinum*)
Main ArteryMaxillary artery (*A. maxillaris*)
Key NerveMaxillary nerve (*N. maxillaris*)

Main Contents

The pterygopalatine fossa houses an essential component of the autonomic nervous system: the pterygopalatine ganglion (Ganglion pterygopalatinum). It is important not to confuse it with other parasympathetic head ganglia (ciliary, submandibular, or otic), which are located in completely different anatomical regions.

Communications via Fissures and Foramina

The fossa features a complex communication network through which major neurovascular bundles pass:

Communications via Canals

In addition to foramina and fissures, the pterygopalatine fossa communicates with neighboring regions through specific canals:

  1. Pterygoid canal (Canalis pterygoideus). Houses the artery of the pterygoid canal (A. canalis pterygoidei), a branch of the maxillary artery. It also transmits the nerve of the pterygoid canal (N. canalis pterygoidei). Interestingly, this nerve is formed by the union of two distinct nerves: the greater petrosal and deep petrosal nerves.
  2. Greater palatine canal (Canalis palatinus major). Transmits the greater palatine nerve (N. palatinus major) and descending palatine artery (A. palatina descendens) inferiorly.

Mnemonic

To remember how the nerve of the pterygoid canal is formed within the fossa, recall that it is assembled from "greater stones" and "deep stones" (the greater and deep petrosal nerves).

Frequently asked questions

What branches does the maxillary nerve give off within the pterygopalatine fossa?

Within the pterygopalatine fossa, the maxillary nerve gives off several key branches:

  • Posterior superior alveolar branches (Nn. alveolares superiores posteriores).
  • Infraorbital nerve (N. infraorbitalis) — continues through the inferior orbital fissure.
  • Zygomatic nerve (N. zygomaticus) — also enters the inferior orbital fissure.
  • Ganglionic branches (Rr. ganglionares) — run to the pterygopalatine ganglion (Ganglion pterygopalatinum).
  • Lateral and medial superior posterior nasal branches (Rr. nasales posteriores superiores laterales et mediales) — exit through the sphenopalatine foramen.
Where does the greater palatine canal open, and what vessels and nerves does it transmit?

The greater palatine canal transmits the greater palatine nerve (N. palatinus major) and the descending palatine artery (A. palatina descendens).

Which ganglion is located in the pterygopalatine fossa?

Only the pterygopalatine ganglion (Ganglion pterygopalatinum) is located here. The ciliary, submandibular, and otic ganglia lie outside this region.

Through which opening does the maxillary nerve enter the fossa?

The maxillary nerve (N. maxillaris) enters the pterygopalatine fossa via the foramen rotundum.

What is the nerve of the pterygoid canal formed by?

The nerve of the pterygoid canal (N. canalis pterygoidei) is formed by the junction of the greater petrosal nerve and the deep petrosal nerve.

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