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Pressure in the Heart Chambers

For medical students2 min readUpdated 2026-10-10

Throughout the cardiac cycle, blood pressure levels in the heart chambers constantly change, ensuring continuous and directed blood flow. The primary driver of this process is the cyclical pressure gradient between the atria, ventricles, and great vessels.

VolumeThe end-diastolic volume of the ventricles reaches 125 mL before contraction begins.
MaximumIn the left ventricle, pressure values can sharply rise from zero to 120 mm Hg.
IncisuraA specific notch on the aortic pressure curve that occurs when the aortic valve closes.
End of SystoleFollowing atrial contraction, pressure in the left ventricle is up to 10 mm Hg.

Hemodynamic Changes and Atrial Function

Normal hemodynamics begin with a pressure gradient. When the pressure in the atria predictably rises, blood rushes into the ventricles, filling their cavities. This process is crucial for preparing the heart for the subsequent powerful ejection.

By the end of atrial systole, baseline pressure values are established in the chambers. In the right ventricle, it reaches up to 5 mm Hg, while in the left ventricle, this figure is slightly higher, reaching up to 10 mm Hg. At the same moment, the blood volume in the ventricles increases to its maximum value. This metric is called the end-diastolic volume (EDV) and is normally equal to 125 mL.

Blood Pressure in the Left Ventricle

On the cardiac cycle graph, left ventricular pressure is typically displayed as a dotted line (Curve III). This curve demonstrates the most significant and sharp pressure fluctuations in the entire cardiovascular system.

Depending on the specific phase of the cycle (systole or diastole), pressure values within the left ventricular cavity can range from minimal values close to 0 mm Hg to a maximum of 120 mm Hg. It is this colossal differential that provides sufficient force to eject blood into the systemic circulation.

Aortic Pressure Dynamics

Aortic blood pressure (Curve I) reflects arterial pressure changes directly at the left ventricular outflow tract. The graph highlights several key elements, each corresponding to a specific mechanical event:

Left Atrial Pressure

Unlike the ventricles and aorta, blood pressure in the left atrium (Curve II, often designated by a dashed line) lacks sharp spikes. The graph reflects only low-amplitude pressure oscillations. This is because the atria primarily function as blood reservoirs and conduits, without generating strong resistance or high pressure.

Mnemonic

To remember the elements of the aortic curve, use the mnemonic ACID: Anacrota (up), Catacrota (down), Incisura (notch), Dicrota (rebound).

Frequently asked questions

What is the maximum systolic pressure in the right ventricle?

The normal maximum systolic pressure in the right ventricle reaches 15–30 mm Hg (with the ejection pressure into the pulmonary trunk being 25–30 mm Hg).

What phases and periods are included in ventricular systole?

Ventricular systole includes two main periods, each divided into phases:

  • Period of tension (isometric contraction) — consists of the asynchronous contraction phase and the isometric contraction phase.
  • Period of blood ejection — consists of the rapid ejection phase and the reduced (slow) ejection phase.
What is the end-systolic volume (ESV) of the ventricles, and what is its normal value?

End-systolic volume (ESV) is the residual volume of blood remaining in the ventricle after its contraction (systole) finishes. Normally, the ESV is about 60 mL (though graphical representations may indicate around 50 mL).

What is the end-diastolic volume of the ventricles?

Normally, the end-diastolic volume (EDV) is 125 mL. This is the maximum volume of blood before ventricular contraction begins.

What pressure is recorded in the ventricles at the end of atrial systole?

In the right ventricle, it reaches a maximum of 5 mm Hg, and in the left ventricle, up to 10 mm Hg.

What are the incisura and dicrotic wave on the aortic pressure graph?

The incisura is a notch indicating the closure of the aortic valve. The dicrotic wave is the subsequent small pressure rise caused by blood rebounding against the closed valve cusps.

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