AMTS ≤ 8 or disorientation in place, time, or person
Urea > 7 mmol/L
Respiratory rate ≥ 30/min
BP: SBP < 90 or DBP ≤ 60 mm Hg
Age ≥ 65 years
About this score
CURB-65 is a short prognostic score for assessing the severity of community-acquired pneumonia (CAP), developed by W. S. Lim et al. (Thorax, 2003) based on a multicenter study of three patient cohorts in the United Kingdom, New Zealand, and the Netherlands. The acronym stands for Confusion, Urea (blood urea), Respiratory rate, Blood pressure, and age 65 years or older — each feature present scores 1 point.
The score addresses the central question at presentation: where to treat a patient with pneumonia — as an outpatient, on a general ward, or in the intensive care unit. According to the original study, 30-day mortality is approximately 1.5% at a score of 0–1, 9% at a score of 2, and 22% at a score of 3 or higher. Major society guidelines for community-acquired pneumonia, including IDSA/ATS, recommend CURB-65 alongside PSI as a standard severity-stratification tool.
The main advantage of CURB-65 is its simplicity: 5 parameters, none of which require anything beyond routine biochemistry. This makes it convenient for use in the emergency department and outpatient settings. The simplified CRB-65 variant (without the urea criterion) is used in the prehospital setting and where laboratory testing is not readily available.
When to use
Initial triage of an adult patient with confirmed or probable community-acquired pneumonia in the emergency department.
Deciding the site of care: outpatient, general medical ward, or ICU.
Documenting severity in the medical record and justifying hospitalization for insurance purposes.
Teaching residents and students clinical reasoning in the management of pneumonia (a standard of clinical propaedeutics).
Reassessment at 24-48 hours to detect deterioration and escalate care.
Parameters in detail
Confusion
Acute confusion: disorientation in time, place, or person, or an Abbreviated Mental Test Score (AMTS) ≤ 8. Chronic cognitive impairment in older adults is not counted on its own — what matters is an acute change.
Urea > 7 mmol/L
Serum urea > 7 mmol/L (equivalent to BUN > 19 mg/dL in English-language sources). Reflects dehydration and renal impairment in the setting of infection.
Respiratory rate ≥ 30/min
Respiratory rate ≥ 30/min — an independent predictor of severity in patients with pneumonia. Must be counted over a full minute, not extrapolated from 15 seconds.
BP: SBP < 90 or DBP ≤ 60 mm Hg
Systolic BP < 90 mm Hg OR diastolic BP ≤ 60 mm Hg. Either criterion alone is sufficient. Baseline hypotension in the patient is not a reason to disregard this criterion.
Age ≥ 65 years
Age ≥ 65 years at the time of assessment. The age criterion accounts for immunosenescence, multimorbidity, and reduced functional reserve.
Clinical example
Case
A 72-year-old man is brought in by EMS with cough, dyspnea, and confusion over the past 2 days. On examination: BP 85/55 mm Hg, respiratory rate 32/min, SpO2 89% on room air, temperature 38.7°C. AMTS score is 6. Labs: urea 9.2 mmol/L, creatinine 142 µmol/L. Chest X-ray shows right-sided lobar infiltration.
High risk, 30-day mortality ~22%. Immediate ICU admission is indicated, with fluid resuscitation, respiratory support, and empiric broad-spectrum antibiotic therapy. qSOFA and SOFA should also be assessed in parallel to rule out septic shock.
Limitations and cautions
Not validated for immunocompromised patients (HIV, chemotherapy, glucocorticoids).
Not intended for hospital-acquired (nosocomial) pneumonia — other scores are used instead (e.g., IDSA/ATS criteria).
In young patients with severe pneumonia, the score may underestimate severity because age contributes little — clinical judgment takes priority over the score.
Does not replace assessment of oxygenation: SpO2 and pO2 are not directly included; significant respiratory failure can occur despite a low score.
Should be used with caution in pregnant patients: physiologic tachypnea and hypotension may distort the result.
What is the difference between CURB-65 and CRB-65?
CRB-65 is a simplified version without the urea criterion (4 parameters). It is used in the prehospital setting and in outpatient practice where biochemistry is not available. Sensitivity is slightly lower, but stratification remains clinically acceptable.
Can CURB-65 be used in a patient with COVID-19 pneumonia?
Yes, but with a caveat: in viral pneumonia the score may underestimate severity, because some patients develop critical hypoxemia without marked changes in consciousness or hemodynamics ("silent hypoxia"). Always combine it with SpO2 and a NEWS2 assessment.
What should be done with a score of 2 points?
Intermediate risk (~9% mortality) requires an individualized decision. Short-stay hospitalization or observation in a short-stay unit is considered, taking into account multimorbidity, social circumstances, and the presence of complications (pleural effusion, bacteremia).
How often should CURB-65 be recalculated?
At a minimum, 24-48 hours after admission and with any clinical deterioration. A progressively rising score is a reason to escalate therapy and consider ICU transfer regardless of the initial stratification.
Does chronic dementia count as confusion?
No. Only an acute change from the patient's baseline cognitive status is counted. In a patient with underlying dementia, the assessment relies on history from relatives: "worse than usual."
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Aleksandr A. Aulov
Physician, internal medicine, Sechenov School — independent medical education platform.
Calculators are compiled from the original publications and current clinical guidelines. Interpretation thresholds follow the source study unless stated otherwise.
This calculator is intended for healthcare professionals. Do not use it for self-diagnosis or self-treatment. Management decisions are made by the treating clinician based on the full clinical picture of the individual patient.
Last clinical review: April 28, 2026 ·
Author: Aleksandr A. Aulov,
MD, internal medicine ·
Primary source: Lim WS et al. Thorax 2003; 58: 377-382