Assessment of disability after stroke
Primary source: van Swieten JC et al. Stroke 1988; 19(5): 604-607
The modified Rankin Scale (mRS) is a global measure of functional disability after stroke. Developed by J. Rankin (1957) and modified by C. Warlow (1988). Used to assess outcome in the first 30-90 days after stroke and at subsequent time points.
The scale has 7 grades (0-6): 0 — no symptoms; 1 — symptoms present but do not affect daily activities; 2 — slight disability (able to carry out daily activities without assistance); 3 — moderate disability (requires some help, walks independently); 4 — moderately severe disability (unable to walk without assistance, unable to manage self-care); 5 — severe disability (bedridden, requires constant care); 6 — death.
The mRS is the primary endpoint in nearly all stroke clinical trials. A "good outcome" is usually defined as mRS 0-2 at day 90. The ESO 2021 guidelines for ischemic stroke use the mRS as the standard measure for evaluating the efficacy of thrombolysis, thrombectomy, and rehabilitation.
A 67-year-old woman, 90 days after an ischemic stroke in the left middle cerebral artery territory. Received thrombectomy 4 hours after symptom onset. At assessment: mild dysarthria, walks independently, cooks and cares for herself, but tires more easily than before and cannot go shopping alone (uses a taxi).
Symptoms present and affect usual activities (needs help with shopping), but self-care is preserved and she walks independently → mRS 2.
Slight disability (mRS 2). This is a "good functional outcome" by accepted criteria. Recommendations: continue secondary prevention (antiplatelet therapy or anticoagulation for atrial fibrillation, statin, blood pressure control), outpatient neurorehabilitation, speech therapy if dysarthria persists.
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